ABCC1

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ABCC1

A gene on 16p13.1 that encodes a protein of the MRP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which transport various molecules across extra- and intracellular membranes, many of which are involved in multidrug resistance. ABCC1 is a transporter of multispecific organic anions, glucuronides and sulfate conjugates of steroid hormones and bile salts; it mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, methotrexate, antivirals and other xenobiotics, and confers resistance to anticancer drugs.
References in periodicals archive ?
The deliberate abolition of the ABCC by the former Labor Government has, according to the FWBC, seen the disregard for the law that defined the industry in Victoria and Western Australia spread to South Australia, Queensland and New South Wales, Senator Abetz said.
The investigator noted that neither person was listed in ABCC records as an officer or director.
Price, also the vice president for ABCC, says many of UConn's urban students weren't afforded the same high school resources as other students.
Despite its protestations, the ABCC is more interested in crushing union influence on job sites than in increasing productivity or, more importantly, protecting workers.
When ABCC conducts enforcement operations and compliance checks, we find that in many cases, the clerk selling the alcohol to the underage person was himself under 21 -- in other words one of the primary problems we find is kids selling alcohol to kids.
Using a Cray supercomputer, ABCC played a critical role in solving the 3-D structure of HIV-1 protease, an enzyme that HIV utilizes to infect human immune cells.
The ABCC also said that the UAE exports to Brazil almost doubled from $309 million in 2012 to $610 million in 2013, while Qatar and Egypt exports stood at $581 million and $276 million, respectively.
Dr Michel Alaby, general secretary and CEO of the ABCC, said: "The Arab countries have been key trade partners of Brazil for a long time, with flourishing bilateral trade continuing to expand over the years.
The state ABCC also must approve the Depot Square Deli license before any alcoholic beverages can be sold there.
The project is led by the umbrella company BrazUKa in association with local cultural organisations Batala, Movema, ABCC and Knotty Ash Community Centre with the support of VIVA Brazil Restaurants.
Secretary-general and chief executive of the ABCC Dr Afnan Al Shuaibi welcomed Shaikh Mohammed's visit, saying that it not only assists the chamber in attaining its goals of serving Arab and British business interests, but it also contributes to re-energising and developing the C global economy.
The fact that over 100 workers have already been dragged before the ABCC and threatened with imprisonment should not be forgotten.