ABCB5

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ABCB5

A gene on chromosome 7p21.1 that encodes an ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins, which participates in ATP-dependent transmembrane transport of a range from small ions, sugars and peptides to complex biomolecules.

Molecular pathology
The ABCB5 protein product is responsible for the doxorubicin resistance in some malignant melanomas.