ABCB4

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ABCB4

A gene on chromosome 7q21.1 that encodes a membrane-associated protein of the superfamily of ATP-binding cassette (ABC) transporters, MDR/TAP subfamily, which is involved in multi-drug resistance and antigen presentation. ABCB4 encodes a transporter and member of the p-glycoprotein family of membrane proteins, which may be involved in transport of phospholipids from hepatocytes into bile.