AATF


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AATF

Apoptosis Antagonizing Transcription Factor. A 523-amino acid nuclear phospoprotein which interacts with ZIPK, a nuclear serine/threonine-specific protein kinase, the overexpression of which induces apoptotic cell death. AATF is encoded by a gene that maps to 17q11.2-q12, the expression of which is downregulated by TGF-beta in intestinal cells. AATF is expressed in cortical neurones and neural PC12 cells and is neuroprotective. Overexpression of AATF protects against amyloid beta-peptide-induced apoptosis in PC12 cells.
Normal expression Brain, heart, thymus, kidney, placenta, skeletal muscle, colon
Abnormal expression Overexpressed in aggressive osteosarcomas
References in periodicals archive ?
The partnership between Arcadia and AATF is designed to solve both of these issues," said Eric Rey, president and CEO of Arcadia.
The license granted by Arcadia presents an opportunity for smallholder farmers to access technologies that will address low rice productivity characterized by low soil nitrogen and high soil salinity and AATF will share these technologies with research institutions and seed multipliers in Africa to ensure that farmers benefit from these technologies,'' he added.
After Arcadia completes the transformation of NUE and Salt Tolerant African Rice, AATF will work with its regional development partners to breed rice varieties that are most effective for local environmental conditions and then distribute to local growers.
To accomplish specific tasks as it implements its portfolio, AATF is looking for a qualified and experienced Project Manager, Cowpea.
Operational management: In consultation with AATF management, manage the financial and administrative aspects of the project and ensure integration of its technical, regulatory and product deployment elements.
Adjustments to the AATF for tax on kerosene used in aviation were made during fiscal year 2010 and were mathematically correct.
The MLA and CEFR documents draw upon basic tenets already present in the ACTFL Standards or 5 C's (and more specific language documents such as those from the AATF and ILR) but further discuss, define, and nuance (1) the long-term humanistic motivations and curricular implications for sustaining these goals and (2) what these goals entail for learners in terms of their interconnected competencies.
In the case of French culture, the AATF National Commission on Cultural Competence (1995) has proposed three cultural categories for understanding culture: empathy, ability to observe and analyze, communication in cultural context (verbal and nonverbal).
They have the expertise, resources and experience with these important traits that can speed the development of improved African rice and get them into the hands of the region's farmers who need them," said Jennifer Thomson, interim executive director of AATF.
As a member of the AATF, he has first-authored numerous IDSA position papers and review articles relating to public policy of antibiotic resistance and antibiotic development.
Salary and benefits will be in line with those provided within AATFs IRS scheme.