5 HK

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5 HK

A highly conserved viral gene encoded by African swine fever virus (ASFV), which is an orthologue of mammalian Bcl-2, the protein product of which, p21, suppresses apoptotic cell death in various settings (e.g., that induced by growth factor deprivation in the mammalian lymphoid cell line) and cells (e.g., HeLa cells and the human myeloid leukemia cell line K562).