CHN1

(redirected from A-chimaerin)

CHN1

A gene on chromosome 2q31.1 that encodes chimerin 1, a GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurones and plays a key role in neuronal signal transduction.

Molecular pathology
CHN1 mutations are linked to Duane’s retraction syndrome type 2.