A2

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A2

aortic second sound.

ATP6V0A2

A gene on chromosome 12q24.31 that encodes a subunit of H+-ATPase (also known as V-ATPase, vacuolar ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles, which is required for an array of molecular processes, including protein sorting, zymogen activation, receptor-mediated endocytosis and synaptic vesicle proton gradient generation.

Molecular pathology
ATP6V0A2 mutations cause cutis laxa type II and wrinkly skin syndrome.

A2

aortic second sound (see heart sounds).
References in periodicals archive ?
Based on Fitch's improved projections of total principal and interest proceeds to be paid to the class A-2 notes, the DR rating on the notes has been revised to 'DR2' from 'DR4'.
The class B notes would receive payments on their principal only after the class A-2 notes are paid in full.
Distributions on Classes I S-1, I A-1, I A-2 and I B-1 will be made from payments received on the mortgage loans in Group I.
Distributions of interest from mortgage loans in loan group 1 will be paid sequentially to the Class A-1, Class A-2 (to the extent not paid by loan group 2), Class B, Class C, Class D, Class E, Class F and Class G certificates up to the stated certificate rate for each class.
Distributions on Classes II S, II A-1, II A-2, and II B-1 will be made from payments received on the mortgage loans in Group II.
The 2006 series A-2 bonds, are expected to be sold through negotiation on or about March 23, 2006.
In response to the rights offering, Occam received subscriptions to purchase 343,741 shares of Series A-2 Preferred Stock for an aggregate purchase price of $3,437,410.
Each subscription right will entitle the stockholder to subscribe for and purchase one share of Series A-2 preferred stock for each 109 shares of common stock held on the record date.
62,218,890 class A-2 notes upgraded to 'A+' from 'BB-';
The class A-2 notes are wrapped by MBIA Insurance Corp.
The class A-1 overcollateralization (OC) ratio, class A-2 OC ratio and class B OC ratio have decreased from 112.
JSDC), courts facility lease revenue bonds (New York City-Jay Street Project), consisting of $90,000,000 fiscal 2001 series A-1 bonds and $45,000,000 fiscal 2001 series A-2 bonds, and will affirm the rating assigned to JSDC's $45,000,000 fiscal 2001 series A-3 bonds.