CCL17

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CCL17

A gene on chromosome 16q13 that encodes a CC-type cytokine, which is characterised by two adjacent cysteines and, as with all cytokines, is involved in immunoregulatory and inflammatory processes. CCL17 binds CCR4 and CCR8, is chemotactic for T cells (but not monocytes or granulocytes), and plays key roles in T-cell development in thymus and in the trafficking and activation of mature T cells.