ADAMTSbg16

(redirected from A Disintegrin and Metalloprotease with Thrombospondin Motifs 16)

ADAMTSbg16

An ADAMTSs family enzyme encoded by ADAMTS16 on chromosome 5p15, which has high sequence similarity to the protein encoded by ADAMTS18. ADAMTS16 is expressed in fetal lung and kidney, and adult brain. Its overexpression in chondrosarcoma cells leads to decreased cell proliferation and migration, though not adhesion, as well as decreased MMP-13 expression.
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