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7-dehydrocholesterol

   Also found in: Wikipedia 0.01 sec.
7-dehydrocholesterol /7-de·hy·dro·cho·les·ter·ol/ (de-hi″dro-kŏ-les´ter-ol) a sterol present in skin which, on ultraviolet irradiation, produces vitamin D.
activated 7-dehydrocholesterol  cholecalciferol.

7-de·hy·dro·cho·les·ter·ol (-d-hdr-k-lst-rôl, -rl)
n.
A provitamin present in the skin of humans as well as the milk of mammals that becomes vitamin D3 when exposed to ultraviolet light.


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Because of the effect of sunlight on 7-dehydrocholesterol in the skin, vitamin D levels are affected by such variables as season, geographic location, population ethnicity, and gender.
3] The multistep biochemical pathway from acetoacetyl-CoA to cholesterol includes 7-dehydrocholesterol as its immediate precursor (Figure 1).
Older individuals are at greater risk for deficiency, because aging lowers the amount of 7-dehydrocholesterol in the skin and thus the ability to produce vitamin D, as well as lower absorption.
 
 
 
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