6-phosphofructokinase


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6-phos·pho·fruc·to·ki·nase

(fos'fō-frŭk'tō-kī'nās),
Phosphofructokinase I; an enzyme that catalyzes the phosphorylation of d-fructose 6-phosphate by ATP (or other NTP) to fructose 1,6-bisphosphate and ADP (or other NDP); this enzyme catalyzes a step in glycolysis; it is inhibited by elevated levels of either ATP or citrate; a deficiency of this enzyme can lead to hemolytic anemia.
Synonym(s): phosphohexokinase

6-phosphofructokinase

/6-phos·pho·fruc·to·ki·nase/ (-frook″to-ki´nās) an enzyme catalyzing the phosphorylation of fructose 6-phosphate, a site of regulation in the Embden-Meyerhof pathway of glucose metabolism; deficiency of the muscle isozyme causes glycogen storage disease, type VII.