The predominant drug related adverse events with 5alpha-reductase inhibitors
are reproductive events, that is typically decreased libido, impotence and ejaculatory dysfunction.
Moreover, standard treatments for BPH symptoms, such as alpha blockers and 5alpha-reductase inhibitors
, can cause sexual dysfunction.
Are Men on 5alpha-Reductase Inhibitors Appropriately Referred to Urology?
Marked Suppression of Dihydrotestosterone in Men With Benign Prostatic Hyperplasia by Dutasteride, a Dual 5alpha-Reductase Inhibitor.
The effects of 5alpha-reductase inhibitors on the natural history, detection and grading of prostate cancer: current state of knowledge.
Effect of the dual 5alpha-reductase inhibitor dutasteride on markers of tumor regression in prostate cancer.
Drug Insight: 5alpha-reductase inhibitors
for the treatment of benign prostatic hyperplasia.