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reductase
(redirected from 5alpha-reductase)

   Also found in: Dictionary/thesaurus, Wikipedia 0.01 sec.
reductase /re·duc·tase/ (-tās) a term used in the names of some of the oxidoreductases, usually specifically those catalyzing reactions important solely for reduction of a metabolite.
5α-reductase  an enzyme that catalyzes the irreversible reduction of testosterone to dihydrotestosterone; enzyme deficiency leads to a form of male pseudohermaphroditism.

re·duc·tase (r-dkts, -tz)
n.
An enzyme that promotes reduction of an organic compound.

reductase [re-duk´tās]
an enzyme that catalyzes a chemical reduction.
5α-reductase an enzyme that catalyzes the irreversible reduction of testosterone to dihydrotestosterone.

reductase
an enzyme that catalyzes a chemical reduction.

5α-reductase
an enzyme that catalyzes the irreversible reduction of testosterone to dihydrotestosterone.


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Saw Palmetto is an herbal DHT inhibitor often claimed to be cheaper and have fewer side effects than finasteride and dutasteride; unlike other 5alpha-reductase inhibitors, saw palmetto induces its effects without interfering with the cellular capacity to secrete PSA (protein specific antigen).
The rationale for inhibiting 5alpha-reductase isoenzymes in the prevention and treatment of prostate cancer.
Effect of the dual 5alpha-reductase inhibitor dutasteride on markers of tumor regression in prostate cancer.
 
 
 
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