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An intermediate in the degradation of l-tryptophan and serotonin.
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Melatonin and 5-methoxytryptamine in non-metazoans.
29) Yu et al (27) found that CYP2D6 may be an additional pathway to regenerate serotonin through 0-demethylation from 5-methoxytryptamine, but it is unclear what proportion of the physiologic pool of serotonin in synaptic nerve terminals is generated through the CYP2D6 pathway.
Inhibition of the in vitro pituitary response to luteinizing hormone-releasing hormone by melatonin, serotonin and 5-methoxytryptamine.

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