5-hydroxytryptamine


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serotonin

 [ser″o-to´nin]
a hormone and neurotransmitter, 5-hydroxytryptamine (5-HT), found in many tissues, including blood platelets, intestinal mucosa, pineal body, and central nervous system; it has many physiologic properties, including inhibition of gastric secretion, stimulation of smooth muscles, and production of vasoconstriction.

ser·o·to·nin

(ser'ō-tō'nin),
A vasoconstrictor, liberated by blood platelets, that inhibits gastric secretion and stimulates smooth muscle; present in relatively high concentrations in some areas of the central nervous system (hypothalamus, basal ganglia), and occurring in many peripheral tissues and cells and in carcinoid tumors.
[sero- + G. tonos, tone, tension, + -in]

5-hydroxytryptamine

/5-hy·droxy·tryp·ta·mine/ (5-HT) (-trip´tah-mēn) serotonin.

5-hydroxytryptamine (5-HT)

See serotonin.

ser·o·to·nin

(ser'ŏ-tō'nin)
A vasoconstrictor, liberated by platelets; inhibits gastric secretion and stimulates smooth muscle; also acts as a neurotransmitter; present in the central nervous system, many peripheral tissues and cells, and carcinoid tumors.
Synonym(s): 5-hydroxytryptamine.
[L. serum + G. tonos, tone, tension, + -in]

5-hydroxytryptamine

See SEROTONIN.

serotonin

; 5-hydroxytryptamine; 5-HT vasoconstrictor phospholipid; liberated by platelets, and present in high concentrations in central nervous system and peripheral tissues; also inhibits gastric secretions

ser·o·to·nin

(ser'ŏ-tō'nin)
A vasoconstrictor, liberated by platelets; inhibits gastric secretion and stimulates smooth muscle; also acts as a neurotransmitter; present in the central nervous system, many peripheral tissues and cells, and carcinoid tumors.
Synonym(s): 5-hydroxytryptamine.
[L. serum + G. tonos, tone, tension, + -in]

5-hydroxytryptamine

serotonin.
References in periodicals archive ?
Monoamine oxidase inhibition as a sequel of hydrogen sulfide intoxication: Increases in brain catecholamine and 5-hydroxytryptamine levels.
3]H]8-hydroxy-2-(di-n-propylamino)tetralin binding to pre- and postsynaptic 5-hydroxytryptamine sites in various regions of the rat brain.
The effect of intraluminal application of 5-hydroxytryptamine and 5-hydroxytryptophan on peristalsis, the local production of 5-hydroxytryptamine and its release in relation to intraluminal pressure and propulsive activity.
3] Nonstandard abbreviations: MDMA, 3,4-methylenedioxy-methamphetamine; MDA, 3,4-methylenedioxy-amphetamine; KIMS, kinetic interaction of microparticles in solution (assay); mCPP, m-chlorophenylpiperazine; 5-HT, 5-hydroxytryptamine.
Triptans, which are 5-hydroxytryptamine receptor agonists used to treat migraine; and SSRIs and SNRIs, used to treat depression and other mood disorders, are serotonergic drugs.
In the rat brain, tamoxifen has been shown to restore 5-hydroxytryptamine (5-FIT) receptor levels (which are decreased after ovariectomy) in the striatum only, whereas treatment with estradiol or raloxifene restores 5-HT receptor density in cingulate and frontal cortices, stratum, and nucleus accumbens.
Strongly (Effexor, inhibits norepinephrine and 5-hydroxytryptamine (5-HT) Effexor-XR) reuptake and weakly inhibits dopamine reuptake.
Other central mechanisms include an increase of plasma tryptophan-branched chain amino acids ratio that results in increased synthesis of 5-hydroxytryptamine, a central neurotransmitter.
Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension.
com/prnh/20130307/600769) Triptans consist of a class of drugs called selective 5-hydroxytryptamine subtype 1 (5-HT1) receptor agonists.
Content and subcellular localization of catecholamines and 5-hydroxytryptamine in human and animal blood platelets: monoamine distribution between platelets and plasma.