5-flucytosine

5-flucytosine

a fluorinated pyrimidine used as a systemic antifungal agent in the treatment of severe candidal and cryptococcal infections.
References in periodicals archive ?
During the following weeks, patients are then given cycles of an oral medication, 5-flucytosine (5-FC), an antifungal drug that readily enters the brain.
2]O) showed evidence of yeast; she was given liposomal amphotericin B and 5-flucytosine and was transferred to a referral hospital, where she received a lumbar puncture to drain CSF and endotracheal intubation for mechanical ventilation in the intensive care unit.
In vitro interaction of terbinafine with itraconazole, fluconazole, amphotericin B and 5-flucytosine against Aspergillus spp.
Etkenin kandida oldugu vakalarda intravenoz amfoterisin B ile birlikte 5-flucytosine veya flukonazol onerilmekte (13), ek olarak yapilan calismalarda intraventrikuler konvansiyonel amfoterisin B (0.
In the absence of 5-flucytosine, the writers believe that southern African patients should be treated with the higher dose of amphotericin B 1 mg/kg/dose.
5 Caspofungin [greater than or equal to]16 Fluconazole [greater than or equal to]64 Voriconazole [less than or equal to]2 MIC, minimal inhibitory concentration; 5-FC, 5-flucytosine.
7-1 mg/kg/day 6-10 weeks healthy host plus 5-flucytosine 100 mg/kg/day 6-10 weeks Alternative Therapy amphotericin B 0.
The patient was treated with liposomal amphotericin B and 5-flucytosine for 4 weeks for disseminated C.
Uchida said, "Over the past two years, we have extended our portfolio of FDA-cleared products, introducing a number of new IVD plates, including a Gram-positive plate used in MRSA detection, which is FDA-cleared for D-Test and Cefoxitin screening, and YeastOne plates available with five IVD-cleared antifungal compounds: itraconazole, fluconazole, 5-flucytosine, voriconazole, and caspofungin.
The patients are usually treated with amphotericin B and 5-flucytosine.
Severe disease can be treated with 200-400 mg/day itraconazole in combination with 5-flucytosine (500 mg/kg per day).