5'-deoxyadenosylcobalamin

(redirected from 5-deoxyadenosylcobalamin)

5'-de·ox·y·a·den·o·syl·co·bal·a·min

(dē-oks'ē-ă-den'ō-sil-kō-bal'ă-min),
An active coenzyme form of vitamin B12; required in the conversion of methylmalonyl-CoA to succinyl-CoA. A deficiency of 5'-deoxyadenosylcobalamin produces methylmalonic acidemia.
References in periodicals archive ?
The biologically active coenzyme forms of vitamin B12 that play a role in human metabolism are methylcobalamin and 5-deoxyadenosylcobalamin (commonly known as adenosylcobalamin).
Its two metabolically active forms, methyl-cobalamin and 5-deoxyadenosylcobalamin, are coenzymes in the reactions catalyzed, respectively, by methionine synthase and methylmalonyl-CoA mutase.