5-alpha reductase inhibitor

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5-alpha reductase inhibitor

A medication to treat benign prostatic hyperplasia. It blocks the conversion of testosterone to dihydrotestosterone.
See also: inhibitor
References in periodicals archive ?
The decrease in PSA in the Se-SM group shows that prophylaxis due to the Se-SM combination may be as effective as 5-alpha-reductase inhibitor treatment (Tindall and Rittmaster, 2008).
Clinical usefulness of serum prostate specific antigen for the detection of prostate cancer is preserved in men receiving the dual 5-alpha-reductase inhibitor dutasteride.
The dual 5-alpha-reductase inhibitor dutasteride induces atrophic changes and decreases relative cancer volume in human prostate.
At the time of presentation, his medications included a 5-alpha-reductase inhibitor (dutasteride) and his anti-Parkinsonian medications (levodopa and the dopamine agonist pramipexole).
Approximately half were randomly assigned to take the 5-alpha-reductase inhibitor finasteride and half to take placebo for 7 years.
The Prostate Cancer Prevention Trial prospectively evaluated finasteride, a 5-alpha-reductase inhibitor, as chemoprevention.
But if a man is taking either Proscar or Propecia or another 5-alpha-reductase inhibitor, the lab report will show it.
Many of us will reach for an alpha-adrenergic antagonist or a 5-alpha-reductase inhibitor as first-line therapy for patients with mild but annoying symptoms.
Dutasteride and finasteride, another 5-alpha-reductase inhibitor, were shot down as prostate chemoprevention agents in December 2010 by the FDA's Oncologic Drugs Advisory Committee on the basis that the risk-benefit profile for either drug is not favorable when it is used to reduce the risk of prostate cancer.
The report finds that physicians and urologists are increasingly prescribing both an alpha blocker and a 5-alpha-reductase inhibitor for patients who exhibit lower urinary tract symptoms and an enlarged prostate.
Nephrology and urology segment is further divided into diuretic drugs, anti-hypertensive agents, phosphate binders, anti-cholinergic agents and 5-alpha-reductase inhibitors.
4] The mainstay of medical treatments includes alpha-blockers, 5-alpha-reductase inhibitors (5-ARIs), or a combination of the two.

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