5-alpha reductase inhibitor


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5-alpha reductase inhibitor

A medication to treat benign prostatic hyperplasia. It blocks the conversion of testosterone to dihydrotestosterone.
See also: inhibitor
References in periodicals archive ?
In the haste of today's busy medical practices, we are concerned that huge numbers of men who could benefit enormously from 5-alpha reductase inhibitors will not be prescribed them.
That body of evidence provided proof" that the 5-alpha reductase inhibitors will decrease the risk of prostate cancer in men being regularly screened for the disease, Dr.
alpha-blockers, 5-alpha reductase inhibitors, or antimuscarinics) depending on the initial assessment.
Second, the Food and Drug Administration (FDA) ruled against the use of 5-alpha reductase inhibitors (ARIs) for prostate cancer prevention, largely due to concerns about an increase in high-grade cancer.
5-alpha reductase inhibitors block formation of the hormone that fuels the growth of the prostate with the goal of preventing the continued growth of the prostate.
This is where cytoreduction comes in; 5-alpha reductase inhibitors (5-ARIs), antiandrogens + 5-ARIs or LHRHa can provide 17, 31 and 40% volume reductions with variable degrees of libido loss, fatigue and hot flashes.
Introduced in the United States last July, it is the first of a new class of drugs -- called 5-alpha reductase inhibitors -- for treating the disease.
Proscar is the first in a new drug class, known as 5-alpha reductase inhibitors.

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