5-alpha reductase inhibitor


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5-alpha reductase inhibitor

A medication to treat benign prostatic hyperplasia. It blocks the conversion of testosterone to dihydrotestosterone.
See also: inhibitor
References in periodicals archive ?
This human failing has caused many physicians and patients to reject 5-alpha reductase inhibitors because they recall something about more high-grade prostate tumors in men taking Proscar[R] or Avodart[R].
That body of evidence provided proof" that the 5-alpha reductase inhibitors will decrease the risk of prostate cancer in men being regularly screened for the disease, Dr.
The ASCO Web site offers physicians a "Decision Aid Tool," composed of charts and diagrams to help explain the risks and benefits of 5-alpha reductase inhibitors to patients and their families.
To our knowledge, studies examining the efficacy and the adverse effects of the combination therapy of PDE-5 inhibitors with 5-alpha reductase inhibitors have not yet been published.
These include alpha blockers like tamsulosin (Flomax), which provide quick symptom relief, and 5-alpha reductase inhibitors like dutasteride (Avodart), which help shrink the prostate over time.
5-alpha reductase inhibitors (5-ARIs): These drugs halt the advance of BPH by shrinking the prostate, and are particularly beneficial for men with larger prostates.
Medical treatments for BPH include 5-alpha reductase inhibitors (5-ARIs), which block the conversion of testosterone to dihydrotestosterone (DHT) via 5-alpha reductase (5-AR).
Using data from the National Health and Nutrition Examination Survey (NHANES) for 2003-2006, the researchers assessed associations between medication use and log-transformed PSA levels in 1,846 men aged 40 years or older who had a serum PSA measurement; did not have a history of prostate cancer, prostatitis, or recent prostate manipulation; and were not taking 5-alpha reductase inhibitors or hormone therapy.
alpha-blockers, 5-alpha reductase inhibitors, antimuscarinics) and physiotherapy.
Men were asked to take one of the 5-alpha reductase inhibitors or a placebo in a double-blind, randomized, controlled study over a number of years.
In the treatment of benign prostatic hyperplasia (BPH), there are several widely utilized medical therapies such as alpha-blockers and 5-alpha reductase inhibitors and occasionally antimuscarinics that have become standard therapies in the clinical practice guidelines.
A Finasteride (Proscar) and dutasteride (Avodart) belong to a class of drugs known as 5-alpha reductase inhibitors (5-ARIs).

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