5-alpha reductase deficiency


Also found in: Wikipedia.

5-alpha reductase deficiency

an autosomal recessive form of partial male pseudohermaphroditism due to a deficiency of type II isoenzyme of 5 5-alpha reductase.
References in periodicals archive ?
Wilson wrote a pivotal paper published in 1974 in The New England Journal of Medicine, in which he wrote that men with a rare genetic disorder -- 5-alpha reductase deficiency -- did not develop normal prostates or prostatic enlargement.
Roehrborn, who has been involved in the testing of Proscar, wrote a paper last fall about dutasteride, a drug developed by GlaxoSmithKline that is also designed to replicate the effects of 5-alpha reductase deficiency.
Full browser ?