5-Sep

5-Sep

A gene on chromosome 22q11.21 that encodes septin 5, a member of the septin family of nucleotide-binding proteins, which regulate cytoskeletal organisation; their disruption alters cytokinesis and results in multinucleated giant cells.

Molecular pathology
SEPT5 maps to 22q11, the same region that is deleted in DiGeorge and velocardiofacial syndrome. Translocation involving SEPT5 and MLL may occur in patients with acute myeloid leukaemia.
References in periodicals archive ?
Jun 5-Sep 22 Erika Vogt: Stranger Debris Roll Roll Roll
Meadows Theatre Big Tops, Aug 5-Sep 3 TOMMY TIERNAN THE former Perrier-winning comic returns to Edinburgh with side-splitting tales about his childhood, the Church and eating a bulldog's laxative tablets
EUROPEAN TOUR DATES 5-Sep FRI ROTTERDAM 8-Sep MON BELFAST 10-Sep WED LONDON 12-Sep FRI ZARAGOZA 13-Sep SAT MADRID 15-Sep MON MALLORCA 17-Sep WED BARCELONA 19-Sep FRI TENERIFE SATELLITE FEED: Friday, September 5, 2008 6:30 PM - 6:45 PM Uplink contact: +31.