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5-hydroxyindoleacetic acid

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5-hydroxyindoleacetic acid /5-hy·droxy·in·dole·ace·tic ac·id/ (-in″dōl-ah-se´tik) a product of serotonin metabolism present in increased amounts in the urine in patients with carcinoid tumors.
5-hydroxyindoleacetic acid
[hīdrok′sē·in′dōlē·əset′ik]
an acid produced by serotonin metabolism, measured in the blood and urine to aid in the diagnosis of certain kinds of tumors. It commonly rises above normal levels in whole blood in association with asthma, diarrhea, rapid heartbeat, and other symptoms and is elevated in the urine of patients with carcinoid syndrome. Its normal concentration in whole blood is 0.05 to 0.20 g/mL; its normal accumulation in urine after 24-hour collection is 1 to 5 mg.

5-hydroxyindoleacetic acid [hi-drok″se-in″dōl-ah-se´tic]
a product of serotonin metabolism excreted in large amounts in patients with carcinoid tumors. Abbreviated 5-HIAA.


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Effect of tryptophan administration on tryptophan, 5-hydroxyindoleacetic acid and indoleacetic acid in human lumbar and cisternal cerebrospinal fluid.
Third, serotonin is largely metabolized to 5-hydroxyindoleacetic acid (5-HIAA), before being excreted in the urine.
5-hydroxyindoleacetic acid (5-HIAA) levels in the cerebrospinal fluid in consciousness and unconsciousness after head injury.
 
 
 
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