concentrations in the pineal tissue of animals from the SN (196 [+ or -] 59 pg/mg of tissue) photoperiod compared with levels in control ewes (419 [+ or -] 45 pg/mg of tissue).
Pharmacological manipulations of the activity of 5-HT
in the CNS induced changes in physical performance, which supports the theory of participation of this neurotransmitter in the central fatigue mechanisms.
The level of 5-HT
in serum and levels of 5-HT
, 5-H[sub]2AR, and SERT in platelets were assayed by enzyme-linked immunosorbent assay (ELISA), as recommended by the Immuno-Biological Laboratory.
The changes in dialysate concentrations of NAc DA and 5-HT
subsequent to the administration of MA and morphine alone or together were expressed as a proportion (percentage) of the corresponding basal value for each mouse.
Selective serotonin reuptake inhibitors, including paroxetine, increase the extracellular concentrations of brain 5-HT
, which can promote the release of dopamine through the stimulation of the 5-HT
3 receptors (Nakayama, 2002).
has been shown to be important in producing pedal wave locomotion in Helix lucorum.
Blocking the reuptake of NE and 5-HT
in the pre-synaptic adrenergic nerve results in increased EUS contractility secondary to increased stimulation of the post-synaptic 5-HT
and NE receptors.
Immunofluorescence Localization of GABA, 5-HT
, and DA in Nerve Ganglia
6 Previous studies have suggested that administration of TRP, the dietary precursor of 5-HT
, increases brain 5-HT
levels and improves memory functions.
3, 4-Methylenedioximethamphetamine (MDMA) is a strong monoaminergic reuptake inhibitor with an extremely high affinity for 5-HT
system is extremely complex, including at least 14 receptor subtypes.
reuptake inhibitors are used as weight reducing agents .