However, ratio of dCK and cytosolic 5'-nucleotidase
II (cN-II), which inactivates Ara-C by dephosphorylation, has been shown to predict ara-C sensitivity.
Short-term zinc supplementation in women with non-insulin-dependent diabetes mellitus: effects on plasma 5'-nucleotidase
activities, insulin-like growth factor I concentrations, and lipoprotein oxidation rates in vitro.
Lipid peroxidation is followed by loss of structural integrity of plasma membranes thereby releasing the membrane associated enzymes like Adenosine deaminase and 5'-nucleotidase
into the circulation.
is an intrinsic membrane glycoprotein, present as an ectoenzyme in a wide variety of mammalian cells and it hydrolyzes extracellular AMP to adenosine and represents the major control point for extracellular adenosine levels and is a regulator of the adenosine signaling pathway.
s case of pyrimidine 5'-nucleotidase
deficiency and heterozygous [alpha]-thalassemia was an interesting co-existence (1).
In the second assay, 5'-Nucleotidase
activity was determined using the [[sup.
activity is altered by hypo- and hyperthyroidism in platelets from adult rats.
This treatment also caused an inhibition of 5'-nucleotidase
and [gamma]-glutamyl-transferase activity are used to confirm liver-specific origin of alkaline phosphatase.
Each of the thiopurine riboside monophosphates (TIMP, thioguanosine monophosphate, and methyl-TIMP) can be converted into thiopurine ribonucleotide triphosphates (8, 9) and dephosphorylated into thiopurine ribonucleosides [mercaptopurine riboside (rMP), mercaptoguanosine riboside (rTG), and MMP riboside (rMMP)] by 5'-nucleotidase
For this reason, it is often useful to measure another enzyme not found in these organs, either the 5'-nucleotidase
(5'-NT) or the gamma-glutamyl transpeptidase (GGTP), along with the alkaline phosphatase when the origin of the elevated alkaline phosphatase (normal < 115 IU/1) is not clear.
Reliability of serum 5'-nucleotidase
alkaline phosphatase and liver scan in hepatic metastasis.