beta-sarcoglycan

(redirected from 43-kD dystrophin-associated glycoprotein)

beta-sarcoglycan

A 43-kD transmembrane glycoprotein of the sarcoglycan complex, which binds to the C-terminal of dystrophin and contributes to the membrane cytoskeleton of myofibres. It is encoded by SGCB on chromosome 4q12, and is defective in patients with limb-muscle muscular dystrophy type 2E.
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