4-aminopyridine


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4-aminopyridine

1. a central nervous system stimulant and a pharmacological antagonist to d-tubocurarine and ketamine-diazepam. Used experimentally as a neuromuscular potentiator in the treatment of botulism.
2. a bird repellent which will poison animals that eat the treated grain accidentally. Horses show fright, sweating, convulsions and sudden death.
References in periodicals archive ?
Ampyra is an oral, sustained-release tablet formulation of 4-aminopyridine.
Fatigue in progressive multiple sclerosis: results of a randomized, doubleblind, placebo-controlled, crossover trial of oral 4-aminopyridine.
Differential effects of 4-aminopyridine on acetylcholine release triggered by [K.
Significantly, in vivo application of compounds of the instant invention established, on the basis of SSEP testing, that the compounds provide longer lasting effects at lower concentrations than comparable treatment with the known agent 4-aminopyridine.
NRI), a biopharmaceutical company focused on treatments for peripheral neuropathies, has announced that its request for orphan drug designation of 4-Aminopyridine has been granted for treatment of chronic functional motor and sensory deficits resulting from Guillain-Barre Syndrome (GBS).
Acorda Therapeutics (Hawthorne, NY) announced preliminary results of a phase II clinical trial of Fampridine-SR, an oral, sustained-release formula of 4-aminopyridine, to treat MS symptoms.
This randomized, double-blind, placebo-controlled study examined the efficacy and safety of 4-aminopyridine (4-AP).
Also used as catalysts were 4-pyrrolidinopyridine and polyDMAP (polymer-bound 4-aminopyridine from Reilly Industries, Inc.
The drug 4-aminopyridine partially restores some sensory and motor functions in one-third of patients who have been paralyzed for months to years.
6b Substance P, bethanechol, 4-aminopyridine, and potassium
In addition, an experimental drug, 4-aminopyridine, appears to increase the velocity of impulses in demyelinated nerves.