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3-nitropropionic acid

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3-nitropropionic acid
one of the nitro compounds in Astragalus spp. which are precursors to neurotoxins in the plant.


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Neuronal degeneration can be caused by the mitochondrial toxin 3-nitropropionic acid (3-NPA) and produce anatomical changes similar to those in Huntington's disease.
Hence in the present study we have addressed primarily two questions (i) whether dietary intake of CA leaf powder posses the propensity to modulate endogenous oxidative markers in mouse brain regions and (ii) the efficacy of CA aqueous extract to abrogate 3-nitropropionic acid (3-NBA)-induced oxidative stress in brain mitochondria in vitro.
In their shoots, the horseshoe vetch and some of its relatives build up high concentrations of a toxic, nitrogen-containing compound called 3-nitropropionic acid (3NPA).
 
 
 
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