HMG-CoA

(redirected from 3-hydroxy-3-methylglutaryl CoA)
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HMG-CoA

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Caffeic acid and chlorogenic acid significantly inhibited fatty acid synthase, 3-hydroxy-3-methylglutaryl CoA reductase and acyl-CoA:cholesterol acyltransferase activities, while they increased fatty acid beta-oxidation activity and peroxisome proliferator-activated receptors alpha expression in the liver compared to the high-fat group.
Another autosomal recessive inborn error of metabolism is 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) lyase deficiency (HMGCLD; OMIM 246450).

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