acridine orange

(redirected from 3 6-BisDimethylamino Acridinium Chloride)
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ac·ri·dine or·ange

(ak'ri-dēn ōr'enj), [C.I. 46005]
3,6-bis(dimethylamino)acridine hydrochloride; a basic fluorescent dye useful as a metachromatic stain for nucleic acids; also used in screening cervical smears for abnormal and malignant cells, where unusual amounts of DNA and RNA occur during proliferation and in tumors (DNA fluoresces yellow to green; RNA fluoresces orange to red).
An immunologic fluorochrome—fluorescent dye—that nonspecifically binds to RNA (red fluorescence), DNA (green fluorescence), proteins, polysaccharides, glycosaminoglycans
Toxicology AO is carcinogenic, causing mutations by intercalating itself within replicating DNA causing insertional or deletional (‘frame shift’) mutations; AO is not routinely used in histologic laboratories

ac·ri·dine or·ange

(ak'ri-dēn awr'ănj)
[CI 46005] A basic fluorescent dye useful as a metachromatic stain for nucleic acids; also used in screening cervical smears for abnormal and malignant cells.