PDE8B

(redirected from 3',5' cyclic nucleotide phosphodiesterase 8B, hsPDE8B)

PDE8B

A gene on chromosome 5q13.3 that encodes a cAMP-specific cyclic nucleotide phosphodiesterase, which hydrolyses the second messenger cAMP to AMP and thus plays a role in regulating physiological processes.

Molecular pathology
PDE8B mutations are linked to autosomal dominant striatal degeneration.