cysteamine

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cysteamine

 [sis-te´ah-mēn″]
a sulfhydryl amine that is part of coenzyme A; it reduces intracellular cystine levels and is used in treatment of nephropathic cystinosis; administered orally.

cys·te·a·mine

(sis-tā'a-mēn),
2-Aminoethanethiol; a sulfhydryl compound used experimentally to produce ulcers in rats and as a radioprotective agent; antidote to acetaminophen.

cysteamine

[siste′ämēn′]
a sulfhydryl amine that is part of coenzyme A. It reduces intracellular cystine levels and is used in treatment of nephropathic cystinosis. It is administered orally.

cysteamine

A stable aminothiol and metabolite of the amino acid cysteine.

Physiologic role
Cysteamine forms coenzyme A by combining with pantothenate and adenosine triphosphate.

Potential therapeutic role
Cysteamine has been in clinical trials for managing Batten disease, cystinosis, non-alcoholic steatohepatitis and Huntington's disease.

cysteamine

Mercaptamine, a drug used to treat NEPHROPATHIC CYSTINOSIS and prescribable only by urological specialists. A brand name is Cystagon.
References in periodicals archive ?
4) were reduced to Fab' 1-21 fragments with 2-mercaptoethylamine hydrochloride (final concentration, 100 mmol/L; final pH, 6.
micro]], SH with 50 mmol/L 2-mercaptoethylamine (Sigma) in phosphate-buffered saline (PBS) containing 10 mmol/L EDTA at 37'C for 1 h, and was separated from 2-mercaptoethylamine by size exclusion HPLC on a TSKgel [G3000SW.
Fab' was then prepared by reduction with 10 mmol/L 2-mercaptoethylamine in 0.

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