2-ketoadipic acid dehydrogenase complex

2-·ke·to·a·dip·ic ac·id de·hy·dro·gen·ase com·plex

the multienzyme complex that reacts 2-ketoadipic acid with coenzyme A and NAD+ to produce glutaryl-CoA, CO2, and NADH + H+ in l-lysine and l-tryptophan catabolism; a deficiency of one of the proteins in this complex results in 2-ketoadipic acidemia.
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