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dioxin
(redirected from 2,3,7,8-tetrachlorodibenzo-p-dioxin)

   Also found in: Acronyms, Encyclopedia, Wikipedia, Hutchinson 0.10 sec.
dioxin /di·ox·in/ (-ok´sin) any of the heterocyclic hydrocarbons present as trace contaminants in herbicides; many are oncogenic and teratogenic.
di·ox·in (d-ksn)
n.
Any of several carcinogenic or teratogenic heterocyclic hydrocarbons that occur as impurities in petroleum-derived herbicides.

Dioxin
A toxic chemical found in weed killers that has been linked to the development of endometriosis.
Mentioned in: Endometriosis

dioxin
[dī·ok′sin]
a contaminant of the herbicide 2,4,5-trichlorophenoxyacetic acid, widely used throughout the world in forestry, on grassland, against woody shrubs and trees on industrial sites, and for rice and sugarcane weed control. Because of its toxicity it is no longer manufactured in the United States. Exposure to dioxin is associated with chloracne and porphyria cutanea tarda. Dioxin was a contaminant of the jungle defoliant Agent Orange sprayed by the U.S. military aircraft over areas of Southeast Asia from 1965 to 1970. Also called 2,3,7,8-tetrachlorodibenzo-para-dioxin.

dioxin
a highly toxic and teratogenic chlorinated hydrocarbon that is a trace contaminant in the herbicide 2,4,5-T. Acute poisoning causes vomiting, abortion, anestrus. Chronic poisoning causes liver damage, especially in dogs. Congenital defects caused include cranio-facial deformity and anasarca. It is excreted in the milk.

dioxin
Toxicology Any of a family of highly toxic chlorinated hydrocarbons Clinical In humans, intense chronic exposure causes weight loss, myalgias, insomnia, dyspnea, cold intolerance, irritability, peripheral neuropathy, hepatomegaly, hemorrhagic cystitis, chloracne, actinic elastosis, loss of libido, impotence Lab ↑ PT, ↑ lipid levels. See Agent Orange, Times Beach.


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Source: Adapted from "Draft Exposure and Human Health Reassessment of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) and Related Compounds," Volume 3, Chapter 3, Table 3-56, U.
The most toxic and notorious member of the family is 2,3,7,8-tetrachlorodibenzo-p-dioxin, or TCDD, widely known as the contaminant in the Vietnam War herbicide Agent Orange.
Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is associated with increased risk for cancer, diabetes, and reproductive toxicities in numerous epidemiologic studies (Schecter and Gasiewicz 2003).
 
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