It may appear at first glance that having 2,4-D
in a flask of a child's urine on a lab bench is not such a big deal.
The effect of 2,4-D
was investigated in seed germination, seedling establishment and root elongation using Petri dishes with the hormone residues (2,4-D
), residue-free new (Clean) and decontaminated (Decontamin) plates.
Results showed a significant delay in development of Drosophila exposed to 3mM 2,4-D
Based on studies addressing endocrine effects on wildlife species and the adequacy of personal protective equipment for workers, the Agency concluded that the science behind our current ecological and worker risk assessments for 2,4-D
is sound and there is no basis to change the registrations.
While USDA attempts to assure the public that 2,4-D
is safe, the science has raised serious concerns about the safety of this herbicide, which was used as a key ingredient in "Agent Orange," used to defoliate forests and croplands in the Vietnam War.
CONCLUSIONS: Biomonitoring data from these studies indicate that current exposures to 2,4-D
are below applicable exposure guidance values.
This conclusion supports the 2005 and 2007 draft assessments issued by PMRA, which found that 2,4-D
can be used safely on lawn, turf, agricultural, forestry and industrial sites, when label directions are followed.
The increase in proliferation after 2,4-D
and MPCAP exposure supports our hypothesis that MCPA and 2,4-D
stimulate growth in low concentration although this effects needs to be confirmed with a second method to determine proliferation.
Subsequent tests in wells near other lakes treated with 2,4-D
showed no similar tainting with the chemical.
RESULTS: Median urine 2,4-D
concentrations at baseline and day after application were 2.
The dog study "suggests that the human health implications of 2,4-D
exposures in the home environment warrant further investigation," the researchers conclude in the Sept.
INDIANAPOLIS -- Dow AgroSciences announced today that the company has successfully produced 2,4-D
choline in a commercial scale-up setting.