a product of glucose metabolism; binds strongly to deoxyhemoglobin. High concentrations are found in erythrocytes. Regulates oxygen-carrying capacity of hemoglobin.
an enzyme in the Embden-Meyerhof pathway of glycolysis in eyrthrocytes. Inherited deficiency results in a hemolytic anemia. Called also diphosphoglycerate mutase.
the sequence of reactions in erythrocytes which conduct the conversion of glucose to energy. The essential part of the cycle is 2,3-bisphosphoglycerate. Called also Rapoport-Luebering cycle.