17beta-hydroxysteroid dehydrogenase deficiency

17β-hydroxysteroid dehydrogenase deficiency

/17β-hy·droxy·ste·roid de·hy·dro·gen·ase de·fi·cien·cy/ an autosomal recessive disorder of steroidogenesis due to deficiency of the testicular enzyme testosterone 17β-dehydrogenase (NADP+); characterized by male pseudohermaphroditism with postpubertal virilization and sometimes gynecomastia, decreased plasma testosterone, and increased androstenedione.