methyltestosterone(redirected from 17alpha-methyltestosterone)
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A methyl derivative of testosterone, with the same actions and uses, except that it is active when given orally or sublingually. Used in the treatment of hypogenitalism.
methyltestosterone/meth·yl·tes·tos·ter·one/ (-tes-tos´ter-ōn) a synthetic androgenic hormone with actions and uses similar to those of testosterone.
A synthetic methylated derivative of testosterone, C20H30O2, used to treat deficiency of natural testosterone in men and metastatic breast cancer in menopausal women, and also used in combination with esterified estrogens in hormone replacement therapy.
indications It is prescribed in the treatment of testosterone deficiency and in the palliation of female breast cancer.
contraindications Cancer of the male breast or prostate; cardiac, renal, or hepatic disease; hypercalcemia; known or suspected pregnancy; lactation; or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse effects are hypercalcemia, edema, irreversible masculinization of female patients, and jaundice.
methyltestosteroneEndocrinology A 17α-alkylated derivative of testosterone used for androgen replacement therapy Pros Oral Cons Hepatotoxicity–cholestasis, peliosis hepatis, liver tumors. See Androgen replacement therapy.
methyltestosteroneA male sex hormone drug sometimes used to treat severe itching caused by CIRRHOSIS OF THE LIVER.
an orally effective, synthetic form of testosterone.