hydroxylase /hy·drox·y·lase/ (hi-drok´sĭ-lās) any of a group of enzymes that catalyze the formation of a hydroxyl group on a substrate by incorporation of one atom (monooxygenases) or two atoms (dioxygenases) of oxygen from O2.
hydroxylase [hi-drok´sĭ-lās]
11β-hydroxylase an enzyme that catalyzes the hydroxylation of steroids at the 11 position, a step in the synthesis of steroid hormones; deficiency causes a form of congenital adrenal hyperplasia.
17α-hydroxylase an enzyme that catalyzes the oxidation of steroids at the 17 position, steps in the synthesis of steroid hormones; deficiency causes a form of congenital adrenal hyperplasia and if it occurs during gestation can cause male pseudohermaphroditism.
18-hydroxylase an enzyme that catalyzes several steps in the biosynthesis of aldosterone from corticosteroids; deficiency causes salt wasting.
21-hydroxylase an enzyme that catalyzes the hydroxylation of steroids at the 21 position, a step in the synthesis of steroid hormones; deficiency impairs the ability to produce all glucocorticoids and causes a form of congenital adrenal hyperplasia.
hy·drox·yl·ase (h -dr k s -l s , -lz)n. Any of various enzymes that catalyze the formation of hydroxyl groups by oxidation of the substrate. |
hydroxylase [hi-drok´sĭ-lās]
any enzyme that brings about the coupled oxidation of two donors, with incorporation of oxygen into one of them.
hydroxylase
any enzyme that brings about the coupled oxidation of two donors, with incorporation of oxygen into one of them.
21-hydroxylase
a partial deficiency of the enzyme, in Pomeranian dogs, is thought to cause a dermatosis; histopathological lesions are of cutaneous atrophy; clinical signs include bilateral alopecia of the trunk, caudal thighs, ventral neck.
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