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17-ketosteroids

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17-ketosteroids
'Male' hormones primarily produced by the testes and adrenal cortex–androsterone, DHEA, epiandrosterone, etiocholanolone, 11-keto- and 11-β-hydroxyandrosterone, 11-keto- and 11-β-hydroxyetiocholanolone; serum levels reflect adrenocortical and testicular function ↑ in Adrenal hyperplasia or tumors, testicular tumors, pregnancy, physical or mental stress, polycystic ovarian disease ↓ in Adrenal hypofunction, Klinefelter syndrome, castration, hypothyroidism, anorexia nervosa


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The measurement of 17-ketosteroids in a 24-hr urine specimen is the initial test of choice for the detection of an androgen or estrogen excess.
Urine measurement of excretion of 17-ketosteroids (17-KS) and 17-hydroxycorticosteroids (17-OHCS).
 
 
 
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