17-ketosteroids | definition of 17-ketosteroids by Medical dictionary
Also found in: Acronyms
17-ke·to·ste·roids (17-KS), (kē'tō-stēr'oydz),
Nominally, any steroid with a carbonyl group on C-17; commonly used to designate urinary C19 steroidal metabolites of androgenic and adrenocortical hormones that possess this structural feature.
17-ketosteroids 'Male' hormones primarily produced by the testes and adrenal cortex–androsterone, DHEA, epiandrosterone, etiocholanolone, 11-keto- and 11-β-hydroxyandrosterone, 11-keto- and 11-β-hydroxyetiocholanolone; serum levels reflect adrenocortical and testicular function ↑ in Adrenal hyperplasia or tumors, testicular tumors, pregnancy, physical or mental stress, polycystic ovarian disease ↓ in Adrenal hypofunction, Klinefelter syndrome, castration, hypothyroidism, anorexia nervosa
Any steroids with a ketone group on C-17; commonly used to designate urinary metabolites of androgenic and adrenocortical hormones that possess this structural feature.
References in periodicals archive
The 2 most commonly used assays measure urinary excretion of PT, a urinary metabolite of 17OHP, or 17-ketosteroids
(17-KS), a urinary metabolite of androgens.
Test tube extraction method for the microdetermination of urinary 17-ketosteroids.
Quantitative methods for the routine analysis of 17-ketosteroids and catecholamines.
In endocrinology the time-honored procedures for 17-ketosteroids
and 17-ketogenic steroids were deleted.