deoxycorticosterone

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desoxycorticosterone

 [des-ok″sĭ-kor″tĭ-ko-stēr´ōn]
a mineralocorticoid with no glucocorticoid activity, secreted in small amounts by the human adrenal cortex. It is used with a glucocorticoid for replacement therapy in adrenocortical insufficiency and addison's disease and for treatment of salt-losing adrenogenital syndrome.

de·ox·y·cor·ti·cos·ter·one (DOC),

(dē-oks'ē-kōr'ti-kos'tĕr-ōn),
An adrenocortical steroid, principally a biosynthetic precursor of corticosterone, which occasionally appears in adrenocortical secretions; a potent mineralocorticoid with no appreciable glucocorticoid activity.

deoxycorticosterone

(dē-ŏk′sē-kôr′tĭ-kŏs′tə-rōn′)
n.
A steroid hormone, C21H30O3, secreted by the adrenal cortex or produced synthetically and formerly used to treat adrenal insufficiency.

deoxycorticosterone

Endocrinology An adrenal steroid with potent mineralocorticoid properties, and minimal glucocorticosteroid properties ↑ in Congenital adrenal hyperplasia, Cushing syndrome, primary aldosteronism, low renin HTN, adrenal CA ↓ in Adrenal insufficiency or hypoplasia

de·ox·y·cor·ti·co·ster·one

(dē-oks'ē-kōr-ti-kos'tĕr-ōn)
An adrenocortical steroid, principally a biosynthetic precursor of corticosterone and possibly aldosterone, which rarely appears in adrenocortical secretions; a potent mineralocorticoid with no appreciable glucocorticoid activity.
Compare: bioregulator
Synonym(s): 21-hydroxyprogesterone.

de·ox·y·cor·ti·co·ster·one

(dē-oks'ē-kōr-ti-kos'tĕr-ōn)
Potent mineralocorticoid with no appreciable glucocorticoid activity.

11-desoxycorticosterone, deoxycorticosterone, deoxycortone

one of the mineralocorticoids, adrenocortical steroids which lack a substituent at C-11; has a greater effect on electrolyte metabolism than glucocorticoids. Available pharmaceutically as the acetate (DOCA), which is short-acting, and the pivalate (DOCP), a slow release form for use in the treatment of hypoadrenocorticism.
References in periodicals archive ?
We could detect no secretion of 11-deoxycorticosterone from these slices.
In slices exposed to tetracosactide, accumulation of corticosterone and 11-deoxycorticosterone in the medium increased linearly for about 48 hr.
11-Deoxycorticosterone secretion from slices exposed to both tetracosactide and metyrapone showed a 6-fold increase (p [is less than] 0.
8%) but worst with methylprednisolone (50%), 11-deoxycortisol (S) (16%), 11-deoxycorticosterone (DOC) (27%), and triamcinolone (13%).