de·ox·y·cor·ti·cos·ter·one (d - k s-kôrt -ks t -r n)n. A steroid hormone produced synthetically or by the adrenal cortex and used to treat adrenal insufficiency. Also called 21-hydroxyprogesterone. |
desoxycorticosterone [des-ok″sĭ-kor″tĭ-ko-stēr´ōn]
a mineralocorticoid with no glucocorticoid activity, secreted in small amounts by the human adrenal cortex. It is used with a glucocorticoid for replacement therapy in adrenocortical insufficiency and addison's disease and for treatment of salt-losing adrenogenital syndrome.
11-desoxycorticosterone, deoxycorticosterone, deoxycortone
one of the mineralocorticoids, adrenocortical steroids which lack a substituent at C-11; has a greater effect on electrolyte metabolism than glucocorticoids. Available pharmaceutically as the acetate (DOCA), which is short-acting, and the pivalate (DOCP), a slow release form for use in the treatment of hypoadrenocorticism.
deoxycorticosterone
Endocrinology An adrenal steroid with potent mineralocorticoid properties, and minimal glucocorticosteroid properties ↑ in Congenital adrenal hyperplasia, Cushing syndrome, primary aldosteronism, low renin HTN,
adrenal CA ↓ in Adrenal insufficiency or hypoplasia
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