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deoxycorticosterone
(redirected from 11-deoxycorticosterone)

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
de·ox·y·cor·ti·cos·ter·one (d-ks-kôrt-kst-rn)
n.
A steroid hormone produced synthetically or by the adrenal cortex and used to treat adrenal insufficiency. Also called 21-hydroxyprogesterone.

11-desoxycorticosterone, deoxycorticosterone, deoxycortone
one of the mineralocorticoids, adrenocortical steroids which lack a substituent at C-11; has a greater effect on electrolyte metabolism than glucocorticoids. Available pharmaceutically as the acetate (DOCA), which is short-acting, and the pivalate (DOCP), a slow release form for use in the treatment of hypoadrenocorticism.

deoxycorticosterone
Endocrinology An adrenal steroid with potent mineralocorticoid properties, and minimal glucocorticosteroid properties ↑ in Congenital adrenal hyperplasia, Cushing syndrome, primary aldosteronism, low renin HTN, adrenal CA ↓ in Adrenal insufficiency or hypoplasia


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As measured by HPLC, corticosterone and 11-deoxycorticosterone secretion to the medium increased linearly for at least 24 hr.
 
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