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11-dehydrocorticosterone |
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11-dehydrocorticosterone /11-de·hy·dro·cor·ti·cos·ter·one/ (-kor?ti-kos´ter-on) a steroid produced by the adrenal cortex. 11-dehydrocorticosterone one of the least active of the glucocorticosteroids produced by the adrenal cortex. |
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? Mentioned in | ? References in periodicals archive | |
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In the placenta the fetus is protected from the high
maternal glucocorticoid concentration through the activity of
11[beta]-hydroxysteroid dehydrogenase type 2 (11[beta]-HSD2), which
converts active 11[beta]-hydroxyglucocorticoids (cortisol in human,
corticosterone in rodents) into inactive 11-ketoglucocorticoids
(cortisone in human, 11-dehydrocorticosterone in rodents) (reviewed in
Stewart and Krozowski 1999). |
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11-dehydrocorticosterone
