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11-dehydrocorticosterone

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11-dehydrocorticosterone /11-de·hy·dro·cor·ti·cos·ter·one/ (-kor″tĭ-kos´ter-ōn) a steroid produced by the adrenal cortex.
11-dehydrocorticosterone [de-hi″dro-kor″tĭ-ko-stēr´ōn]
one of the least active of the glucocorticosteroids produced by the adrenal cortex; it affects water and salt metabolism.
11-dehydrocorticosterone
one of the least active of the glucocorticosteroids produced by the adrenal cortex.
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In the placenta the fetus is protected from the high maternal glucocorticoid concentration through the activity of 11[beta]-hydroxysteroid dehydrogenase type 2 (11[beta]-HSD2), which converts active 11[beta]-hydroxyglucocorticoids (cortisol in human, corticosterone in rodents) into inactive 11-ketoglucocorticoids (cortisone in human, 11-dehydrocorticosterone in rodents) (reviewed in Stewart and Krozowski 1999).
Organotins disrupt the 11[beta]-hydroxysteroid dehydrogenase type ... by Odermatt, Alex / Environmental Health Perspectives
The enzyme 11[beta]-hydroxysteroid dehydrogenase type 2 (11[beta]-HSD2) converts corticosterone to 11-dehydrocorticosterone in the distal convoluted tubules and cortical collecting ducts in rats, and cortisol to cortisone in humans.
The effects of supraphysiological levels of cortisol alone or in ... by Adams, Stevie / Journal of the Mississippi Academy of Sciences
 
 
 
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