PIK3R3

(redirected from 100% homology to SWISS-PROT Q925692)

PIK3R3

A gene on chromosome 1p34.1 that encodes a regulatory subunit of phosphoinositide 3-kinase. PIK3R3 binds to activated (phosphorylated) protein-Tyr kinases through its SH2 domain and regulates their kinase activity; it is highly expressed in the brain and testis.
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