-acetoacetyl coenzyme A thiolase | definition of -acetoacetyl coenzyme A thiolase by Medical dictionary
thiolase (redirected from -acetoacetyl coenzyme A thiolase)
an acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis.
thiolase An obsolete generic term for any enzyme (e.g., acetyl CoA acetyltransferase [EC 188.8.131.52]) which catalyses a reaction between a compound, R–R’, and a thiol, R’–SH, forming R–S–R’ and R'–H.