thiolase

a·ce·tyl-CoA a·ce·tyl·trans·fer·ase

an acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis.

Synonym(s): acetoacetyl-CoA thiolase, acetyl-CoA thiolase, thiolase

thiolase

An obsolete generic term for any enzyme (e.g., acetyl CoA acetyltransferase [EC 2.3.1.9]) which catalyses a reaction between a compound, R–R’, and a thiol, R’–SH, forming R–S–R’ and R'–H.