tabes dorsalis

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tabes

 [ta´bēz]
1. wasting of the body or a part of it.
2. tabes dorsalis. adj., adj tabet´ic.
tabes dorsa´lis a slowly progressive nervous disorder, from degeneration of the dorsal columns of the spinal cord and sensory nerve trunks, resulting in disturbances of sensation and interference with reflexes and consequently with movements; called also locomotor ataxia. It is caused by syphilis and may appear 5 to 20 years after initial infection. Its course is slow but progressive; it can often be arrested, but complete cure is rare. The first symptoms are pain in the lower limbs, upper limbs, or trunk, loss of posture sense, and Argyll Robertson pupils (pupils that are uneven and do not react to light). Unless the patient looks down at his legs he does not know where they are and must depend on his vision for each step. The typical gait of a tabetic patient is jerky and wide-based.
tabes mesente´rica tuberculosis of the mesenteric glands in children.

tabes dorsalis

(dôr-sā′lĭs, -săl′ĭs)
n.
A late form of syphilis resulting in a hardening of the dorsal columns of the spinal cord and marked by shooting pains, emaciation, loss of muscular coordination, and disturbances of sensation and digestion. Also called locomotor ataxia.

tabes dorsalis

Etymology: L, tabes, wasting, dorsum, the back
an abnormal condition characterized by the slow degeneration of all or part of the body and the progressive loss of deep tendon reflexes, caused by syphilis. This disease involves the posterior columns and posterior roots of the spinal cord and destroys the large joints of affected limbs in some individuals. A wide-base ataxic gait is usually present. It is often accompanied by incontinence and impotence and severe flashing pains in the abdomen and extremities.

tabes dorsalis

A complication of untreated syphilis consisting of slowly progressive degeneration of the dorsal/posterior columns of the spinal cord, which are seen a decade or more after infection, in late or tertiary phase of syphilis.

Clinical findings
Sharp pain, ataxia, optic-nerve degeneration leading to blindness, urinary incontinence, loss of position sense, joint degeneration (aslo known as Charcot’s joints).

tabes dorsalis

Tabes syphilis, tabetic neurosyphilis Neurology Slowly progressive degeneration of the dorsal/posterior columns of the spinal cord typical of late or tertiary phase of syphilis, which occurs a decade or more after infection, when it is improperly treated Clinical Sharp–lightning pain, ataxia, optic nerve degeneration leading to blindness, urinary incontinence, loss of position sense, joint degeneration, aka Charcot's joints. See Charcot's joints, Syphilis. Cf Friedreich's tabes, Pseudotabes.

ta·bet·ic neu·ro·syph·i·lis

(tă-bet'ik nūr'ō-sif'i-lis)
Type of neurosyphilis in which the posterior roots of the spinal cord, especially in the lumbosacral area, are the principal sites of infection, resulting in ataxia, hypotonia, impotence, constipation, hypotonic bladder, areflexia, and Romberg sign; other findings include lancinating pains (most often in the legs), visceral crises, Argyll-Robertson pupils, optic atrophy, and neuropathic joints. In most patients, the cerebrospinal fluid contains antibodies to Treponema pallidum.
Synonym(s): tabes dorsalis.

tabes dorsalis

Degeneration of the sensory nerve columns in the rear part of the spinal cord caused by untreated SYPHILIS. There are severe, stabbing ‘lightning’ pains in the legs or lower trunk, unsteadiness and a characteristic gait in which the feet are kept well apart, lifted high and stamped forcibly. Joint damage and foot ulcers occur and vision may be affected by optic nerve involvement. Treatment with penicillin can arrest the progress of the disease. Also known as locomotor ataxia.

Tabes dorsalis

A progressive deterioration of the spinal cord and spinal nerves associated with tertiary syphilis.
Mentioned in: Syphilis

tabes dorsalis

; TD chronic inflammation, progressive central and peripheral neural sclerosis, loss of muscular coordination and muscle atrophy, peripheral neuropathy and sensory anaesthesia, neuralgia and lancinating pains, neuroarthropathy (Charcot joint formation) and visceral crises; characteristic of late-stage (tertiary) syphilis

tabes dorsalis 

A degenerative disease of the posterior columns of the spinal cord, the posterior spinal roots and the peripheral nerves accompanied by a number of ocular signs and symptoms such as atrophy of the optic nerve, visual field defects, ptosis, Argyll Robertson pupil and paralysis of one or more of the extraocular muscles. The disease is a result of neurosyphilis.

ta·bet·ic neu·ro·syph·i·lis

(tă-bet'ik nūr'ō-sif'i-lis)
Type of late tertiary syphilis, seen predominantly in men; its major clinical manifestations are ataxia, urinary incontinence, and brief lancinating pains ("lightning pains"), which can affect any portion of the body, but particularly the legs.
Synonym(s): tabes dorsalis.
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