MTRR

(redirected from [methionine synthase]-cobalamin methyltransferase)

MTRR

A gene on chromosome 5p15.31 that encodes an enzyme involved in the reductive regeneration of cob(I)alamin cofactor required for maintaining methionine synthase in a functional state.

Molecular pathology
Defects in MTRR cause methylcobalamin deficiency type E and folate-sensitive neural tube defects.